Smart Water

Discover water you never imagined before...

Whether in cosmetic or healthcare markets, consumers' believes has radically changed: they will definitely go for products ensuring

  • Proven efficacy
  • Natural based
  • No side effects

Adwatis SA provides a new product and technology platform called Advanced Water S-100.

Advanced Water S-100 is an active water consisting in a unique mineralization with high reducibility and semi-permanent stability caused by molecular ions with electron rich state. These molecular ions are characterized as high pH and weak basicity according to Lewis theory. Therefore, Advanced Water S-100 is totally safe and 100% biocompatible with human skin thanks to very weak basicity and specific minerals, providing a unique optimization of human skin cell's ionic balance.


Active water
High degree of efficacy
A new way of formulating

Better performances - unique mechanisms of action.

Advanced Water S-100 as an active component ensuring unique efficacy and top safety for cosmetic & skin repair, such as skincare and cleansing, dermo-cosmetics, haircare as well as for pharmaceutical such as woundcare, burncare, atopic dermatitis. Try it. Amazing.

Pure formulation without compromises

Advanced Water S-100 reshapes the way you develop and design new products thanks to its unique power. As Advanced Water only (diluted) or in combination with a few ingredients. Due to its preservative action, it can go with less sophisticated packaging systems. Furthemore, O/W emulsion with less or no emulsifier is now possible in specific cases for light formulas.

Efficient industrial / filling process

Advanced Water S-100 can help in reducing technical constraints thanks to its unique properties and light formula approach.

 Fascinating Water

Fascinating Water

Water, the chemistry of life

If you thought water was a simple, innocent molecule, think again. Water is from far one of the most fascinating substance on our planet. Water remains one the major mysteries of the Universe. It supports life like no other substance does as chemical reactions in all plants and animals take place in water medium, releasing or consuming water in their metabolism. Life on Earth totally depends on water as living organisms are largely composed of water – about 70 to 90 percent by weight, and above 99 percent by absolute number of water molecules.

Water is vital both as a solvent in which many of the body's solutes dissolve and as an essential part of many metabolic life processes. Without water, these particular metabolic processes could not exist. Most of chemical reactions occur in the cell itself. Water plays a central role in biological and chemical, especially acid-base, processes. Equally important to our comprehension of the structure and dynamics of water is understanding the role it plays as a solvent facilitating long-ranged charge transport of species such as ions, excess protons and hydroxide ions. The excess proton and hydroxide ion, both particularly important in acid-base chemistry and bio-molecular function, plays an important role in the metabolism of all organisms as reflected by the wide variety of chemical reactions in which they take part. Ions are cofactors of enzymes, catalyzing basic functions such as electron transport, redox reactions, and energy metabolism; they are essential for maintaining the osmotic pressure of cells too.


Water, the universal solvent

Water is often referred to as the universal, superb solvent. Mainly due to the marked polarity of the water molecule and its tendency to form hydrogen bonds with other molecules. All of the components in cells (proteins, DNA and polysaccharides) are dissolved in water deriving their structure and activity from their interactions with water. Water dissolves more substances in greater quantities than any other common liquid making water key important in chemical, physical and biological processes.



Oxidation-reduction reactions

Basically, reduction means the addition of an election (e-), and its converse, oxidation means the removal of an electron. The addition of an electron, stores energy in the reduced compound. The removal of an electron, liberates energy from the oxidized compound. Whenever one substance is reduced, another is oxidized. In biological systems, removal or addition of an electron constitutes the most frequent mechanism of oxidation-reduction reactions, frequently called redox reactions.


Water is an acid and a base

Water can be both an acid and a base, depending on how you look at it. Water can even react with itself to form acid and bases. It happens in really small amounts; chemists have determined the concentration of H3O+ at 25°C as being very low: only a few molecules per billion will be dissociated. Dissociation of water forms an acid that increases the concentration of hydrogen ions (hydronium H3O+ also known as hydrated H+) and a base that increases the concentration of hydroxide ions (OH-). This can be amplified by using electrolysis process to drive an otherwise non-spontaneous chemical reaction.

The degree of acidity or alkalinity of a solution is measured in terms of a value known as pH, which is the negative logarithm of the concentration of hydrogen ions. Scientists have defined a pH scale which ranges from 0 on the acidic end to 14 on the alkaline end, a neutral solution being at pH 7. At pH 7 water contains equal concentrations of H+ and OH- ions. Substances with pH higher than 7 are alkaline as having a higher concentration of OH- than H+ and vice versa for acidic substance with pH lower than 7 containing a higher concentration of H+ than OH-. The pH scale is a log scale so a change of 1 pH units means a tenfold change in the concentration of hydrogen ions.

pH values of various substances


 Advanced Water Technology

Advanced Water S-100 Technology

Electrochemically reduced water (ERW)

Alkaline ionized water generated by water electrolysis has constantly received increasing attention due to benefits in treatment and prevention of diseases. Electrolysis of slightly salt water or tap water produces a special water very useful and known as functional electrolyzed water. Various types of functional water can be produced depending on conditions of electrolysis, and these types of water are classified into two major categories. One is functional electrolyzed acidic water, which is generated at the anode; the other one, generated at the cathode, is electrolyzed alkaline water. Both, depending on their properties, are widely used in medical, cosmetic and technical fields.

In Japan, research on functional water, especially on electrochemically reduced water (ERW) also known as electrochemically reduced alkaline water (ERAW), is developing at a rapid pace.

Studies on the functions of ERW were initiated in Japan in the 40’s and its application to agriculture was first attempted in 1954. Six years later, the Ministry of Health, Labor and Welfare of Japan, admitted ERW as effective for human health against various diseases (external & internal) and authorized ERW producing devices as Medical Device. Korean Food & Drug Administration (KFDA) followed a few years later. Today fast accumulating evidences demonstrate how ERW can be health beneficial and active in reducing oxidative stress-related diseases.     


Advanced Water S-100

ADWATIS SA provides a new generation of ionized water, different from traditional alkaline ones, called Advanced Water:

  • Unique, 100% safe and non-chemical electrolytic reduced ionized water.
  • Strong efficacy thanks to high pH and key mineralization with unique properties.
  • Environmentally friendly and nontoxic.
  • Patented JP2007050400

Electrolyzed deoxidized and ionized water S-100 is made out of innovative electrolytic patented process as well as longstanding expertise and know-how. Having a pH of 12, it has about 100’000 times more negative ions than normal water (approx. pH 7). Advanced Water S-100 is stable and effective for 3-4 years. It can be diluted with water or mixed under certain conditions with other ingredients while maintaining ionic properties.

Advanced Water S-100 is an active water consisting in a unique mineralization with high reducibility and semi-permanent stability caused by molecular ions with electron rich state. These molecular ions are characterized as high pH and weak basicity according to Lewis theory. Therefore, Advanced Water S-100 is totally safe and 100% biocompatible with human skin thanks to very weak basicity and specific minerals, providing a unique optimization of human skin cell's ionic balance.


Advanced Water S-100

Standard alkaline waters

  • pH 12, mineralized, low redox value
  • pH 9-10, high redox >-200mV
  • Stable (over 3 years)
  • Very unstable, quick loss of basicity
  • Stable and safe properties thanks to a unique production process.

  • Made out of pure and ultra-filtered water enriched with selected minerals (Na, Si, K, P, Mg, Ca, Cl).

  • Can be diluted with demineralized water while maintaining ionic properties.

  • Advanced Water is a weak base. It is equivalent to 0,04M NH4OH.

  • When in contact with the skin and its organic acids, Advanced Water S-100 is quicly neutralized to skin' slightly acidic natural pH level.

  • Unstable ionic properties which will even vary depending on production process. 

  • Made out of standard tap water without any control on mineral salts.

  • Potential presence of strong bases such as NaOH or KOH (toxic).
    Middle to high basicity.

  • Revert to neutral when diluted.




Unique mechanisms of action

Basic principle: double electric layer. S-100 Water contains negative ions OH-. Once in contact with any kind of surface, material, particles, water ions interact by reorganizing electric charges. The surface remains polarized and actively prevents from any future building up of foreign particles. ("Double electric layer" theory.)


1. Cleansing power

Advanced Water S-100, with its army of negatively charged ions, penetrates, encapsulates all kind of particles such as atoms, molecules, mico-organisms, (...) and removes them by repulsion effect (due to same polarity) from all kind of even or uneven microscopic surfaces. Isolated particles and pollutants are easily removed by rinsing. In case of dermo-cosmetic applications, the same mechanism happens: e.g. skin cleansing where ionic work force interacts between lipids (sebum) and skin producing a so-called repulsion force effect.


Comparison made with "Micellar Water make-up remover" (left) versus Advanced Water S-100 (30% dilution) (right). Drawing made on a tile using "edding 250 whiteboard marker".


2. Antimicrobial power (removes & kills bacteria & viruses)



In case of surface bacterial contamination such as E-coli, the ionization process of S-100 Water quickly polarizes and dislodges the pathogen. Bacteria outer membrane (Gram-) is dissolved by ions force, leading rapidly to the destruction of the cell nucleus, eliminating any chance of re-contamination. Gram+ type bacteria are quickly dislodged by repulsion force. Advanced Water is not a biocide, which is a serious advantage.
Bacteria, even alkaliphilic bacteria which are comfortable with high pH, cannot survive in pH over 10.5. Bacteria growth is therefore impossible under S-100 high pH (11.5 – 12.5). When in contact with the skin and its organic acids, Advanced Water S-100 is quicly neutralized to skin' slightly acidic natural pH level; a second application will keep high pH intact for further antimicrobial action and cell's pH balancing action. In any case, absolutely no negative reaction/stimulation of the skin is observed, as confirmed by several tests and analysis made by well-known European laboratories and research centers, such as:

Patch test 48 hours: non irritant
Human elbow fold test: very good skin compatibility
Challenge Test: A Criteria (pure) / B Criteria (diluted)
Cutaneous/Ocular Safety & Efficiency Assessment: Restores the cutaneous barrier,
strengthens and protects the skin
TEWL (Transepidermal Water Loss): significant reduction
Cleansing against particles: anti-pollution effect
Eye test Het cam: slightly irritant (3)
Stratum corneum test: 100% safe
Proton mobility: very high (2700ms)


3. Cell's ionic balancing

Advanced Water S-100 combines both effects of its high pH and unique mineralization (Na, Si, K, P, Mg, Ca, Cl), structured through a patented electrolytic process, generating unique molecular structures. Advanced Water not only cleans, protects and ensures stressed/damaged skin's pH balance but also plays a key role in supporting cellular's functioning and regeneration (metabolism and ionic balance).

Thanks to an adequate pH and minerals environement, cells can develop and accelerate healing process by reducing inflammation and stimulating vascularization. Combined with its anti-microbial and cleansing effects, Advanced Water S-100 offers a state of the art solution for skincare and woundcare (e.g. burn, ulcers, atopic dermatits, damaged or stressed skin).


100% Safe & non toxic

Thanks to its weak basicity (equivalent to 0,04M NH4OH) Advanced Water S-100 does show respect for natural skin pH as being quicky neutralized when in contact with its natural organic acids. It easily penetrates the different skin's layers without damaging cell's membrane and cutaneous microbiote, unlike surfactants, alcohol, preservatives (...) which presence in most of today cosmetic/OTC formulas seriously denature and damage skin's tissues. Advanced Water is the only safe and original high pH water without any chemicals or harmful ingredients.  


Emulsification through repulsion

In case of light formulas, dispersion of micro-particles of oil in water (10microns or less) being potentially possible thanks to negative ions repulsion process. Less need of emulsifier/solubilizer for oil in water mixing.


 Products & Applications

Advanced Water S-100

is a super ionized alkaline and mineralized water that opens new generation of unequally pure and innovative products in cosmetic and OTC pharma with high performance and unique mechanisms of action:

1. Cleansing Power
2. Antibacterial / Preservative Power
3. Cell's ionic balancing Power

Advanced Water INCI name: Water & Mineral Salts

  • pH of 12 +/- 0.5 without harmful chemicals (bacteria/virus cannot surive over pH 10.5)

  • Safe and non toxic (without KOH and NaOH)

  • Stable over years, can be mixed under certain conditions

  • Environment friendly, Innovative - unequaled to date.

Having a pH of 12 - totally safe an nontoxic - Advanced Water S-100 creates an environment which is incompatible with bacteria and virus. Advanced Water S-100 is a weak base and is equivalent to 0,04M NH4OH in terms of basicity, which makes it totally safe and non aggressive. When in contact with the skin and its organic acids, Advanced Water S-100 is quickly neutralized to skin's natural pH level.

Advanced Water S-100 is totally stable overs years and can be mixed, under certain conditions, in case of "light" formulas, with other products as long as pH value remains high, meaning over 10.50 - 11.00 once stability tests have been completed.

Advanced Water S-100 is made out of highly purified water and 7 key minerals:

  • Sodium and Potassium are the moste important ions for outside / inside the cell.
  • Phosphorus as a key role in autophagy process / immune function.
  • Silicon due to its 4legs structure can create a myriad of substances essential in repairing and regenerating e.g. elastin and fibroplast.
  • Calcium and Magnesium are essential elemens in the metabolism of eukaryotic cell biology. Magnesium as en enzymatic activator as well as calcium as intra-cell regulator.
  • Chlorides generated make sodium and potassium stable and safe.


Advanced Water Gel GE-100

is a highly thixotropic water gel wtih unique emulsification power for a nice gel consistancy. Combined with S-100 , GE-100 makes oil in water emulsion possible wtihout any use of emulsifier by keeping S-100 unique properties. Advanced Water Gel has the same properties as S-100 as being made out of over 96% of Advanced Water S-100.

Advanced Water Gel GE-100 INCI name: Water & Mineral Salts and Sodium Magnesium Silicate and Disodium Phospate

Key features

  • Quickly turns into liquid form after quick shaking and back to gel within 10 seconds.
    Can be easily spray despite high viscosity.
  • Makes unmiscible powder in water possible in GE-100
  • Dispenable as a gel in a spray from (back to gel on the skin)

Emulsification power

Dispersion of micro-droplets of oil in water (10 microns or less) thanks to negative ions repulsion process in specific cases with light formulas. Less or no need of emulsifier/solubilizer for oil in water mixing.


Advanced Water GEL CC6

is a light viscous water gel based on S-100. Can be easily obtained by mixing S-100 Water with 1% CMC Sodium Carboxymethyl Cellulose. Due to its consistancy, very useful for oil in water emulsion in combination with S-100 and GE-100. Can be used alone as a gel by keeping entire S-100 properties.

Example of effectiveness on dental plaque when used as a toothpaste

Principle of cleaning/exfoliation power.
1. Dental plaque build-up on enamel surface.
2. Once in contact with CC6, ionic interactions between molecules attract negative ions on the surface of the dental plaque and enamel.
3. Dental plaque is removed by repulsion force (negative-negative charges)


Bactericidal effect against periodontal bacteria

Made by microscope picture of patient suffering from periodontal desease.
Instruction of use: toothbrushing for approx 2 minutes with 1g of CC6 followed by water rinsing.


Application fields

Technical: hightech & medical cleaners e.g. ultrasonic cleaning, E-tobaco cleaning, (...)

Face & Body (moisturizing mist / cream, pH balancer, impurities, refreshing & care, detox, ...)
Skincare, skin repair, cleansing agent (hygiene, personal hygiene, detox, make-up remover, lotions, serum, skin balancer...)
Dermo-cosmetic (irritated skin, anti-stress, sunburn, cracked skin, ...)
Haircare: (cleansing, hair/skin treatment/preparation before coloring, ...)

Pharma OTC / Veterinary: 
Woudcare (ulcers, burns)
Dermal (acne, irritaded skin, atopic dermatitis)
ORL (nasal lavage, inflamated throat, ear wash (cerumen)
Hémorroïdes (pain relief, healing, anti-bleeding)


Examples of clinical cases

Extracts from single cases (over 1000 cases as of today) and clinical cases' studies. Scientific papers under section "Scientific papers / Tests".
Burn, wound, dermal...


  • Cleaning and detoxifying of open wounds

  • Moisturizing to better support scarring process

  • Healing to prevent infection

  • Restoring of tissue and skin functions.







Thanks to our GAPP Partnership, the French company PB Group ( can provide you with a range of high pH cosmetic products, especially developped with Advanced Water S-100 and its unique properties for more efficacy and without any preservative thanks to S-100 power.

- Detox Cleaning Foam
- Micellar Active Water
- Leave-on Hand Cleansing Gel
- Milky Mist
- Cream (face & body)
- Jelly Scrub

and more...



Advanced Water S-100: Available in 18 liters bag-in-box. 

Advanced Water Gel GE-100: Available in 10 liters bag-in-box. (18 liters on demand)

Advanced Water Gel CC6: Available for sampling (1liter)

 Technical Data / Leaflets







Medical cases



Safety Data Sheets / Specs

Advanced Water S-100

Advanced Water Gel GE-100

Advanced Water Gel CC6


Cosmetic's tests summary / Anti-bacterial tests results / Instructions of use

Bactericidal effect of S-100 and CC-6 against p.gingivalis

Cosmetic's tests summary

Instructions of use S-100 for skincare


ADWATIS SA  |  Boucle de Cydalise 1  |  2300 La Chaux-de-Fonds  |  Switzerland
Boucle de Cydalise 1
2300 La Chaux-de-Fonds